Parkinson disease affects nearly one million people in the United States, and nurses encounter it across virtually every practice setting, from primary care and neurology clinics to medical-surgical units, emergency departments, long-term care, and hospice. Its hallmark motor features of tremor, rigidity, bradykinesia, and postural instability represent only part of a complex clinical picture that also includes cognitive change, mood and sleep disturbances, autonomic dysfunction, and a demanding medication regimen with narrow timing windows. This course provides a thorough clinical foundation in Parkinson disease for the practicing nurse. It traces the disorder from its underlying pathophysiology and genetics through diagnosis, the full pharmacologic and device-assisted treatment landscape, and the management of motor complications and non-motor symptoms that shape quality of life. Particular attention goes to the nursing priorities that carry the greatest impact on patient safety, including on-time medication administration, recognition of contraindicated drugs, and prevention of falls and aspiration, along with support for patients and families through advanced and end-of-life care. Learners will finish prepared to apply this knowledge directly in daily practice.